Fluorescent Lactic Acid Bacteria and Bifidobacteria as Vehicles of DNA Microbial Biosensors

Management and quantification of effector molecules corresponding to heavy metals, toxins or different goal molecules is of nice biotechnological, social and financial curiosity. Microorganisms have regulatory proteins that acknowledge and modify the gene expression within the presence or absence of those compounds (effector molecules) via binding to gene sequences. The affiliation of those recognizing gene sequences to reporter genes will permit the detection of effector molecules of curiosity with excessive sensitivity.

As soon as investigators have these two elements-recognizing gene sequences and reporter genes that emit signals-we want an appropriate automobile to introduce each components. Right here, we propose lactic acid micro organism (LAB) and bifidobacteria as promising service microorganisms for these molecular biosensors. Using fluorescent proteins in addition to food-grade vectors and clustered repeatedly interspaced brief palindromic repeats (CRISPR) are indispensable instruments for introducing biosensors into these microorganisms. Using these LAB and bifidobacteria can be of particular curiosity for learning the intestinal setting or different advanced ecosystems.

The good number of species tailored to many environments, in addition to the opportunity of making use of a number of protocols for his or her transformation with recognizing gene sequences and reporter genes are appreciable benefits. Lastly, an effort should be made to search out recognizable gene sequences.

DNAAF5 Antibody, HRP conjugated
1-CSB-PA771471LB01HU	EUR 317.00 EUR 335.00	100ug 50ug
Description: A polyclonal antibody against DNAAF5. Recognizes DNAAF5 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

DNAAF5 Antibody, FITC conjugated
1-CSB-PA771471LC01HU	EUR 317.00 EUR 335.00	100ug 50ug
Description: A polyclonal antibody against DNAAF5. Recognizes DNAAF5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

DNAAF5 Antibody, Biotin conjugated
1-CSB-PA771471LD01HU	EUR 317.00 EUR 335.00	100ug 50ug
Description: A polyclonal antibody against DNAAF5. Recognizes DNAAF5 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

DNAAF5 Polyclonal Antibody, Biotin Conjugated
A58815	100 µg	EUR 570.55
Description: Ask the seller for details

DNAAF5 Polyclonal Antibody, FITC Conjugated
A58816	100 µg	EUR 570.55
Description: The best epigenetics products

DNAAF5 Polyclonal Antibody, HRP Conjugated
A58817	100 µg	EUR 570.55
Description: kits suitable for this type of research

Human Dynein Assembly Factor 5, Axonemal / HEATR2 (DNAAF5) ELISA Kit
abx387761-96tests	96 tests	EUR 911

CD11b Antibody Antibody
ABD2911	100 ug	EUR 438

H2B Antibody Antibody
AF4659	200ul	EUR 376
Description: H2B Antibody Antibody detects endogenous levels of H2B.

anti- Antibody^Polyclonal antibody control antibody
LSMab09882	100 ug	EUR 438

Antibody
A1360-500		Ask for price

Anti-Anti-SEPT2 Antibody antibody
STJ25475	100 µl	EUR 277

Anti-Anti-SEPT5 Antibody antibody
STJ25477	100 µl	EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody
STJ25479	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody
STJ28365	100 µl	EUR 277

Anti-Anti-SEPT7 Antibody antibody
STJ28963	100 µl	EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody
STJ117206	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody
STJ117759	100 µl	EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody
STJ118549	100 µl	EUR 277

Anti-Anti-MARCH6 Antibody antibody
STJ118550	100 µl	EUR 277

Anti-Anti-MARCH7 Antibody antibody
STJ118752	100 µl	EUR 277

Anti-Anti-SEPT3 Antibody antibody
STJ118990	100 µl	EUR 277

Anti-Anti-SEPT1 antibody antibody
STJ119580	100 µl	EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody
STJ116214	100 µl	EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody
STJ11100949	100 µl	EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody
STJ111369	100 µl	EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody
STJ111530	100 µl	EUR 277

Anti-Anti-SEPT4 Antibody antibody
STJ112276	100 µl	EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody
STJ112609	100 µl	EUR 277

Anti-Anti-SEPT11 Antibody antibody
STJ113941	100 µl	EUR 277

Anti-Anti-SEPT11 Antibody antibody
STJ114081	100 µl	EUR 277

Anti-Anti-SEPT5 Antibody antibody
STJ114819	100 µl	EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody
STJ114828	100 µl	EUR 277

Ly1 Antibody Reactive (LYAR) Antibody
20-abx123734	EUR 411.00 EUR 592.00	100 ul 200 ul

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319900	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319901	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319905	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody
20-abx319913	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Ly1 Antibody Reactive (LYAR) Antibody
20-abx311665	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycolipid Antibody (AGA) Antibody
20-abx004855	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Anti-Glycolipid Antibody (AGA) Antibody
abx036399-100ug	100 ug	EUR 391

Ly1 Antibody Reactive (LYAR) Antibody
20-abx008109	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Ly1 Antibody Reactive (LYAR) Antibody
20-abx014333	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Ly1 Antibody Reactive (LYAR) Antibody
abx033330-400ul	400 ul	EUR 523

Ly1 Antibody Reactive (LYAR) Antibody
abx033330-80l	80 µl	EUR 286

Ly1 Antibody Reactive (LYAR) Antibody
abx234901-100ug	100 ug	EUR 551

Anti-Glycolipid Antibody (AGA) Antibody
abx230204-100ug	100 ug	EUR 481

Ly1 Antibody Reactive (LYAR) Antibody
20-abx324434	EUR 314.00 EUR 244.00	100 ug 50 ug

Monoclonal NGF/proNGF Neutralizing Antibody Antibody
AMM06679G	0.05mg	EUR 528
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Anti CD22 Antibody: CD22 Monoclonal Antibody
065-A-01mg	0,1 mg	EUR 267.5
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody
065-A-1000ug	1000 ug	EUR 1282.5
Description: anti-CD22 monoclonal antibody

Anti-IgG1 Negative Control Antibody antibody
STJ16100881	1 mL	EUR 478

Anti-Noelin Antibody BIOTIN Antibody BIOTIN
STJ501938	100 µg	EUR 586

Anti-Noelin Antibody FITC Antibody FITC
STJ501939	100 µg	EUR 586

Anti-Noelin Antibody BIOTIN Antibody BIOTIN
STJ501940	100 µg	EUR 586

Anti-Noelin Antibody FITC Antibody FITC
STJ501941	100 µg	EUR 586

Antibody for Human alpha Tubulin Antibody
SPC-692D	0.1mg	EUR 354
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A390	0.1mg	EUR 401
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A488	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A565	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 565.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A594	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 594.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A633	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 633.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A655	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 655.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A680	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 680.

Antibody for Human alpha Tubulin Antibody
SPC-692D-A700	0.1mg	EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 700.

Antibody for Human alpha Tubulin Antibody
SPC-692D-ALP	0.1mg	EUR 394
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Alkaline Phosphatase.

Antibody for Human alpha Tubulin Antibody
SPC-692D-APC	0.1mg	EUR 399
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC .

Antibody for Human alpha Tubulin Antibody
SPC-692D-APCCY7	0.1mg	EUR 471
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC/Cy7.

Antibody for Human alpha Tubulin Antibody
SPC-692D-BI	0.1mg	EUR 396
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Biotin.

Antibody for Human alpha Tubulin Antibody
SPC-692D-DY350	0.1mg	EUR 414
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 350.

Antibody for Human alpha Tubulin Antibody
SPC-692D-DY405	0.1mg	EUR 403
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 405.

Antibody for Human alpha Tubulin Antibody
SPC-692D-DY488	0.1mg	EUR 393
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 488.

Antibody for Human alpha Tubulin Antibody
SPC-692D-DY594	0.1mg	EUR 395
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 594.

Antibody for Human alpha Tubulin Antibody
SPC-692D-DY633	0.1mg	EUR 390
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 633.

Antibody for Human alpha Tubulin Antibody
SPC-692D-FITC	0.1mg	EUR 392
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to FITC.

Antibody for Human alpha Tubulin Antibody
SPC-692D-HRP	0.1mg	EUR 388
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to HRP.

Antibody for Human alpha Tubulin Antibody
SPC-692D-P594	0.1mg	EUR 407
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to PE/ATTO 594.

Antibody for Human alpha Tubulin Antibody
SPC-692D-PCP	0.1mg	EUR 399
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to PerCP.

Antibody for Human alpha Tubulin Antibody
SPC-692D-RPE	0.1mg	EUR 397
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to RPE .

Antibody for Human alpha Tubulin Antibody
SPC-692D-STR	0.1mg	EUR 398
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Streptavidin.

Antibody for Human alpha Tubulin Antibody
SPC-692S	0.012mg	EUR 65
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319902	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319903	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319904	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319906	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319907	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319908	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319914	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319915	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)
20-abx319916	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)
20-abx319929	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)
20-abx319930	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Irregular Homocysteine Metabolism: An Perception of Alzheimer’s Illness from DNA Methylation

Alzheimer’s illness (AD) is a persistent neurodegenerative illness within the central nervous system that has advanced pathogenesis within the aged. The present evaluation focuses on the epigenetic mechanisms of AD, in response to the newest findings. The most effective-characterized chromatin modifications in epigenetic mechanisms is DNA methylation. Extremely replicable knowledge reveals that AD incidence is usually accompanied by methylation degree adjustments of the AD-related gene.

Homocysteine (Hcy) is just not solely an intermediate product of one-carbon metabolism but in addition an vital impartial danger issue of AD; it may possibly have an effect on the cognitive perform of the mind by altering the one-carbon metabolism and interfering with the DNA methylation course of, leading to cerebrovascular illness. Usually, Hcy could also be an environmental issue that impacts AD by way of the DNA methylation pathway with a collection of adjustments in AD-related substance. This evaluation will think about the relation between DNA methylation and Hcy and take a look at to determine their rule within the pathophysiology of AD.

TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation

 

Hypoxia-inducible components are heterodimeric transcription components that play an important position in a cell’s capability to adapt to low oxygen. The von-Hippel Lindau tumor suppressor (pVHL), acts as a grasp regulator of HIF exercise, and its focusing on of prolyl hydroxylated HIF-α for proteasomal degradation beneath normoxia is considered a significant mechanism for pVHL tumor suppression and mobile response to oxygen.

Whether or not pVHL regulates different targets by the same mechanism is essentially unknown. Right here, we determine TET2/Three as novel targets of pVHL. pVHL induces proteasomal degradation of TET2/3, leading to decreased international 5-hydroxymethylcytosine ranges.

Conserved proline residues inside the LAP/LAP-like motifs of those two proteins are hydroxylated by the prolyl hydroxylase enzymes (PHD2/EGLN1 and PHD3/EGLN3), which is prerequisite for pVHL-mediated degradation. Utilizing zebrafish as a mannequin, we decided that international 5-hydroxymethylcytosine ranges are enhanced in vhl-null, egln1a/b-double null and egln3-null embryos.

Subsequently, we reveal a novel perform for the PHD-pVHL pathway in regulating TET protein stability and exercise. These knowledge prolong our understanding of how TET proteins are regulated and supply new perception into the mechanisms of pVHL in tumor suppression.

Level-of-care DNA testing by routinely and sequentially performing extraction, amplification and identification in a closed-type cassette

• Nucleic acid detection is vital for scientific diagnostics; nonetheless, it’s difficult to carry out genetic testing on the point-of-care because of the tedious steps concerned in DNA extraction and the chance of cross-contamination from amplicons.

• To realize a fully-automated and contamination-free nucleic acid detection, we suggest a closed-type cassette system which allows the next steps to be operated routinely and sequentially: pattern preparation based mostly on magnetic beads, goal amplification utilizing multiplex polymerase chain response, and colorimetric detection of amplicons utilizing a serial invasive response coupled with the aggregation of gold nanoparticle probes.

• The cassette was designed to be spherical and closed, and 10 targets in a pattern might be concurrently detected by the bare eye or utilizing a spectrophotometer within the system.

• As well as, a cassette-driven system was fabricated to switch reagents between wells, to regulate the temperature of every response, and to sense the color within the detection wells. The cassette system was delicate sufficient to detect 10 genotypes at 5 single nucleotide polymorphism websites associated to the anticoagulant’s utilization, through the use of a 0.5 µL blood pattern.

• The accuracy of the system was evaluated by detecting 12 entire blood samples, and the outcomes obtained have been according to these obtained utilizing pyrosequencing. The cassette is hermetic and the entire system is absolutely computerized; the one guide operation is the addition of the pattern to the cassette, performing point-of-care genetic testing in a sample-in/answer-out means.

Human DNA Ligase 4 (LIG4) ELISA Kit
abx388272-96tests	96 tests	EUR 911

Human DNA ligase 4, LIG4 ELISA KIT
ELI-47684h	96 Tests	EUR 824

Chicken DNA ligase 4, LIG4 ELISA KIT
ELI-47798c	96 Tests	EUR 928

Mouse DNA ligase 4, Lig4 ELISA KIT
ELI-32012m	96 Tests	EUR 865

DNA Ligase 4 Phospho-Thr650 (LIG4 pT650) Antibody
20-abx322874	EUR 314.00 EUR 244.00	100 ug 50 ug

DNA Ligase 4 antibody
70R-35788	100 ug	EUR 327
Description: Rabbit polyclonal DNA Ligase 4 antibody

DNA Ligase 4 antibody
70R-50002	100 ul	EUR 244
Description: Purified Polyclonal DNA Ligase 4 antibody

DNA Ligase 4 Blocking Peptide
20-abx061782	EUR 258.00 EUR 384.00	1 mg 5 mg

DNA Ligase 4 Blocking Peptide
20-abx062877	EUR 272.00 EUR 411.00	1 mg 5 mg

DNA Ligase 4 (DNL4) Antibody
20-abx014021	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

DNA Ligase 4 (pT650) Antibody
abx216563-100ug	100 ug	EUR 439

T4 DNA Ligase (Recombinant)
abx073011-100000IU	100.000 IU	EUR 509

T4 DNA Ligase (Recombinant)
abx073011-20000IU	20.000 IU	EUR 258

T4 DNA Ligase (Recombinant)
abx073011-500000IU	500.000 IU	EUR 1539

Recombinant T4 DNA Ligase
7-03622	20,000IU	Ask for price

Recombinant T4 DNA Ligase
7-03623	100,000IU	Ask for price

Recombinant T4 DNA Ligase
7-03624	500,000IU	Ask for price

DNA Ligase 4 (Phospho-Thr650) Antibody
12457-100ul	100ul	EUR 252

DNA Ligase 4 (Phospho-Thr650) Antibody
12457-50ul	50ul	EUR 187

Phospho-DNA Ligase 4 (Thr650) Antibody
AF8089	200ul	EUR 376
Description: DNA Ligase 4 (Phospho-Thr650) Antibody detects endogenous levels of DNA Ligase 4 only when phosphorylated at Thr650.

DNA Ligase 4 (Phospho- Thr650) Antibody
ABF8089	100 ug	EUR 438

DNA Ligase I (DNA Ligase I) Antibody
abx232431-100ug	100 ug	EUR 481

Recombinant (E.Coli) T4 DNA Ligase
RP-374	20 KU	EUR 164

Phospho-DNA Ligase 4 (Thr650) Blocking Peptide
AF8089-BP	1mg	EUR 195

DNA ligase Antibody
20-abx110554	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

T4 DNA Ligase
abx098136-10kU	10 kU	EUR 321

T4 DNA Ligase
abx098136-20Ku	20 Ku	EUR 398

T4 DNA ligase
402-002	400 WEISS UNITS	EUR 63

T4 DNA ligase
402-010	2000 WEISS UNITS	EUR 154

IL-4 Interleukin 4 Human Recombinant Protein, Yeast
PROTP05112-4	Regular: 10ug	EUR 317
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

DNA Ligase IV recombinant monoclonal antibody
A5820	100ul X 3	EUR 595
Description: A recombinant monoclonal antibody from rabbit against human DNA Ligase IV for WB, IHC, IF,ELISA

100 BP DNA LADDER, 500UL PER KIT
M-DNA-100BP	1/pk	EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT
M-DNA-1KB	1/pk	EUR 70
Description: Bioscience Mol Bio; DNA Ladder

DNA Ligase 4 (Phospho-Thr650) Polyclonal Conjugated Antibody
C12457	100ul	EUR 397

Recombinant Human 4-1BB Receptor Protein
PROTQ07011-4	20ug	EUR 317
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Recombinant Human PF-4 (CXCL4) Protein
PROTP02776-4	20ug	EUR 317
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Human DNA ligase 1 (LIG1)
1-CSB-EP012930HU	EUR 380.00 EUR 214.00 EUR 1309.00 EUR 560.00 EUR 873.00 EUR 262.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human DNA ligase 1(LIG1) expressed in E.coli

DNA ligase 3 antibody
22508-100ul	100ul	EUR 390

DNA ligase 3 antibody
22940-100ul	100ul	EUR 390

DNA ligase IV Antibody
35335-100ul	100ul	EUR 390

DNA Ligase IV Antibody
49667-100ul	100ul	EUR 333

DNA Ligase IV Antibody
49667-50ul	50ul	EUR 239

DNA Ligase I Antibody
49797-100ul	100ul	EUR 333

DNA Ligase I Antibody
49797-50ul	50ul	EUR 239

T4 DNA Ligase (40000U)
9K-005-0002	40000U	EUR 292.73

DNA ligase Antibody (Biotin)
20-abx106283	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

DNA ligase Antibody (FITC)
20-abx107697	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

DNA ligase Antibody (HRP)
20-abx109115	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

DNA Ligase 1 Antibody
20-abx141113	EUR 356.00 EUR 537.00 EUR 217.00	100 ul 200 ul 30 ul

DNA Ligase 3 Antibody
20-abx141114	EUR 356.00 EUR 537.00 EUR 217.00	100 ul 200 ul 30 ul

pUC57- T4 DNA Ligase
PVT10516	2 ug	EUR 266

T4 DNA Ligase Plasmid
PVT7008	2 ug	EUR 512

anti-DNA Ligase I
YF-PA12953	50 ul	EUR 363
Description: Mouse polyclonal to DNA Ligase I

E. coli DNA Ligase
M1217-100		EUR 321

T4 DNA Ligase (Rapid)
N103-01	600,000 U	EUR 563

T4 DNA Ligase Buffer
9102-1		EUR 88

anti-DNA Ligase I
YF-PA24084	50 ul	EUR 334
Description: Mouse polyclonal to DNA Ligase I

anti-DNA Ligase III
YF-PA24085	50 ul	EUR 334
Description: Mouse polyclonal to DNA Ligase III

T4 DNA Ligase protein
30R-2898	250 units	EUR 224
Description: Purified recombinant Human T4 DNA Ligase protein

DNA ligase 3 antibody
70R-12710	100 ul	EUR 457
Description: Affinity purified Rabbit polyclonal DNA ligase 3 antibody

DNA ligase 3 antibody
70R-12712	100 ul	EUR 457
Description: Affinity purified Rabbit polyclonal DNA ligase 3 antibody

Recombinant ATP Dependent DNA ligase I (LIG1)
4-RPB269Hu01	EUR 521.12 EUR 242.00 EUR 1679.20 EUR 626.40 EUR 1152.80 EUR 412.00 EUR 4048.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human ATP Dependent DNA ligase I expressed in: E.coli

Recombinant ATP Dependent DNA ligase I (LIG1)
4-RPB269Ra01	EUR 539.04 EUR 247.00 EUR 1746.40 EUR 648.80 EUR 1197.60 EUR 424.00 EUR 4216.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat ATP Dependent DNA ligase I expressed in: E.coli

Feline IL-4 Recombinant Protein
R00230-4	5ug/vial	EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Recombinant Treponema pallidum p15 (partial)
7-07552	100µg	Ask for price

Recombinant Treponema pallidum p15 (partial)
7-07553	500µg	Ask for price

Recombinant Treponema pallidum p15 (partial)
7-07554	1000µg	Ask for price

Recombinant Treponema pallidum p17 (Partial)
7-07564	100µg	Ask for price

Recombinant Treponema pallidum p17 (Partial)
7-07565	500µg	Ask for price

Recombinant Treponema pallidum p17 (Partial)
7-07566	1000µg	Ask for price

Recombinant Treponema pallidum p47 (Partial)
7-07576	100µg	Ask for price

Recombinant Treponema pallidum p47 (Partial)
7-07577	500µg	Ask for price

Recombinant Treponema pallidum p47 (Partial)
7-07578	1000µg	Ask for price

Recombinant Treponema pallidum TmpA (Partial)
7-07579	100µg	Ask for price

Recombinant Treponema pallidum TmpA (Partial)
7-07580	500µg	Ask for price

Recombinant Treponema pallidum TmpA (Partial)
7-07581	1000µg	Ask for price

DNA Ligase I ELISA KIT|Human
EF009143	96 Tests	EUR 689

Recombinant Human DNA ligase 1 Protein, GST, E.coli-100ug
QP6308-ec-100ug	100ug	EUR 408

Recombinant Human DNA ligase 1 Protein, GST, E.coli-10ug
QP6308-ec-10ug	10ug	EUR 200

Recombinant Human DNA ligase 1 Protein, GST, E.coli-1mg
QP6308-ec-1mg	1mg	EUR 1632

Recombinant Human DNA ligase 1 Protein, GST, E.coli-200ug
QP6308-ec-200ug	200ug	EUR 634

Recombinant Human DNA ligase 1 Protein, GST, E.coli-500ug
QP6308-ec-500ug	500ug	EUR 1060

Recombinant Human DNA ligase 1 Protein, GST, E.coli-50ug
QP6308-ec-50ug	50ug	EUR 263

Supercoiled pHOT-1 DNA
TG2030-4	500 ug	EUR 1052

Relaxed pHOT-1 DNA
TG2035-4	500 ug	EUR 1052

LIG4 Antibody
1-CSB-PA002168	EUR 222.00 EUR 195.00	100ug 50ug
Description: A polyclonal antibody against LIG4. Recognizes LIG4 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

LIG4 Antibody
1-CSB-PA009827	EUR 222.00 EUR 195.00	100ug 50ug
Description: A polyclonal antibody against LIG4. Recognizes LIG4 from Human. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/20000

LIG4 Antibody
1-CSB-PA012932GA01HU	EUR 597.00 EUR 333.00	150ul 50ul
Description: A polyclonal antibody against LIG4. Recognizes LIG4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

LIG4 Antibody
CSB-PA869550-		EUR 335
Description: A polyclonal antibody against LIG4. Recognizes LIG4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

LIG4 Antibody
CSB-PA869550-100ul	100ul	EUR 316
Description: A polyclonal antibody against LIG4. Recognizes LIG4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000