Fluorescent Lactic Acid Bacteria and Bifidobacteria as Vehicles of DNA Microbial Biosensors
Management and quantification of effector molecules corresponding to heavy metals, toxins or different goal molecules is of nice biotechnological, social and financial curiosity. Microorganisms have regulatory proteins that acknowledge and modify the gene expression within the presence or absence of those compounds (effector molecules) via binding to gene sequences. The affiliation of those recognizing gene sequences to reporter genes will permit the detection of effector molecules of curiosity with excessive sensitivity.
As soon as investigators have these two elements-recognizing gene sequences and reporter genes that emit signals-we want an appropriate automobile to introduce each components. Right here, we propose lactic acid micro organism (LAB) and bifidobacteria as promising service microorganisms for these molecular biosensors. Using fluorescent proteins in addition to food-grade vectors and clustered repeatedly interspaced brief palindromic repeats (CRISPR) are indispensable instruments for introducing biosensors into these microorganisms. Using these LAB and bifidobacteria can be of particular curiosity for learning the intestinal setting or different advanced ecosystems.
The good number of species tailored to many environments, in addition to the opportunity of making use of a number of protocols for his or her transformation with recognizing gene sequences and reporter genes are appreciable benefits. Lastly, an effort should be made to search out recognizable gene sequences.
) DNAAF5 Antibody (HRP) |
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| 20-abx308300 | Abbexa |
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) DNAAF5 Antibody (FITC) |
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| 20-abx308301 | Abbexa |
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) DNAAF5 Antibody (Biotin) |
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| 20-abx308302 | Abbexa |
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 DNAAF5 Polyclonal Antibody |
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| A58814 | EpiGentek | 100 µg | EUR 570.55 |
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Description: reagents widely cited |
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 DNAAF5 Antibody, HRP conjugated |
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| 1-CSB-PA771471LB01HU | Cusabio |
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Description: A polyclonal antibody against DNAAF5. Recognizes DNAAF5 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
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 DNAAF5 Antibody, FITC conjugated |
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| 1-CSB-PA771471LC01HU | Cusabio |
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Description: A polyclonal antibody against DNAAF5. Recognizes DNAAF5 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
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 DNAAF5 Antibody, Biotin conjugated |
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| 1-CSB-PA771471LD01HU | Cusabio |
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Description: A polyclonal antibody against DNAAF5. Recognizes DNAAF5 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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 DNAAF5 Polyclonal Antibody, Biotin Conjugated |
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| A58815 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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 DNAAF5 Polyclonal Antibody, FITC Conjugated |
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| A58816 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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 DNAAF5 Polyclonal Antibody, HRP Conjugated |
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| A58817 | EpiGentek | 100 µg | EUR 570.55 |
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Description: kits suitable for this type of research |
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 ELISA Kit) Human Dynein Assembly Factor 5, Axonemal / HEATR2 (DNAAF5) ELISA Kit |
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| abx387761-96tests | Abbexa | 96 tests | EUR 911 |
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 H2B Antibody Antibody |
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| AF4659 | Affbiotech | 200ul | EUR 376 |
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Description: H2B Antibody Antibody detects endogenous levels of H2B. |
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 CD11b Antibody Antibody |
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| ABD2911 | Lifescience Market | 100 ug | EUR 438 |
 anti- Antibody^Polyclonal antibody control antibody |
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| LSMab09882 | Lifescience Market | 100 ug | EUR 438 |
 Antibody) Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx008109 | Abbexa |
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 Antibody) Anti-Glycolipid Antibody (AGA) Antibody |
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| 20-abx004855 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx123734 | Abbexa |
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Anti-Glycolipid Antibody (AGA) Antibody |
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| abx036399-100ug | Abbexa | 100 ug | EUR 391 |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx014333 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| abx033330-400ul | Abbexa | 400 ul | EUR 523 |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| abx033330-80l | Abbexa | 80 µl | EUR 286 |
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 Antibody) Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319900 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319901 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319905 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319913 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| abx234901-100ug | Abbexa | 100 ug | EUR 551 |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx324434 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx311665 | Abbexa |
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Anti-Glycolipid Antibody (AGA) Antibody |
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| abx230204-100ug | Abbexa | 100 ug | EUR 481 |
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 Anti-Anti-SEPT6 antibody antibody |
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| STJ11100949 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
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 Anti-Anti-SEPT9 Antibody antibody |
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| STJ111369 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
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 Anti-Anti-SEPT11 Antibody antibody |
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| STJ111530 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT4 Antibody antibody |
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| STJ112276 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
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 Anti-Anti-SEPT2 Antibody antibody |
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| STJ25475 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT5 Antibody antibody |
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| STJ25477 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
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 Anti-Anti-SEPT8 Antibody antibody |
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| STJ25479 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Anti-Anti-SEPT2 Antibody antibody |
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| STJ28365 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT7 Antibody antibody |
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| STJ28963 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
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 Anti-Anti-MARCH9 Antibody antibody |
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| STJ112609 | St John's Laboratory | 100 µl | EUR 277 |
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Anti-Anti-SEPT11 Antibody antibody |
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| STJ113941 | St John's Laboratory | 100 µl | EUR 277 |
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Anti-Anti-SEPT11 Antibody antibody |
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| STJ114081 | St John's Laboratory | 100 µl | EUR 277 |
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Anti-Anti-SEPT5 Antibody antibody |
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| STJ114819 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
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 Anti-Anti-MARCH8 Antibody antibody |
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| STJ114828 | St John's Laboratory | 100 µl | EUR 277 |
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Anti-Anti-SEPT7 Antibody antibody |
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| STJ116214 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
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Anti-Anti-SEPT8 Antibody antibody |
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| STJ117206 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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 Anti-Anti-SEPT12 Antibody antibody |
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| STJ117759 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. |
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 Anti-Anti-MARCH6 Antibody antibody |
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| STJ118549 | St John's Laboratory | 100 µl | EUR 277 |
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Anti-Anti-MARCH6 Antibody antibody |
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| STJ118550 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-MARCH7 Antibody antibody |
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| STJ118752 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT3 Antibody antibody |
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| STJ118990 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT1 antibody antibody |
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| STJ119580 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] |
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 Cytokeratin 7 antibody-Cytoskeleton Marker Antibody |
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| 48169-100ul | SAB | 100ul | EUR 333 |
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Cytokeratin 7 antibody-Cytoskeleton Marker Antibody |
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| 48169-50ul | SAB | 50ul | EUR 239 |
 Antibody Pair to ApoA-V antibody |
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| 10R-1876 | Fitzgerald | 100 ul | EUR 651 |
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Description: Mouse monoclonal Antibody Pair to ApoA-V antibody |
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 Anti CD22 Antibody: CD22 Monoclonal Antibody |
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| 065-A-01mg | Virogen | 0,1 mg | EUR 267.5 |
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Description: anti-CD22 monoclonal antibody |
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Anti CD22 Antibody: CD22 Monoclonal Antibody |
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| 065-A-1000ug | Virogen | 1000 ug | EUR 1282.5 |
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Description: anti-CD22 monoclonal antibody |
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 Antibody) Hepatitis C Virus Antibody (HCV) Antibody |
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| abx023924-1mg | Abbexa | 1 mg | EUR 1205 |
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 Antibody) Ly1 Antibody Reactive Homolog (LYAR) Antibody |
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| 20-abx103034 | Abbexa |
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Ly1 Antibody Reactive Homolog (LYAR) Antibody |
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| 20-abx103035 | Abbexa |
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Ly1 Antibody Reactive Homolog (LYAR) Antibody |
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| 20-abx103036 | Abbexa |
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 Monoclonal NGF/proNGF Neutralizing Antibody Antibody |
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| AMM06679G | Leading Biology | 0.05mg | EUR 528 |
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Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E |
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 Antibody) Anti Deoxyribonucleic Acid Antibody (DNA) Antibody |
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| abx411057-50ug | Abbexa | 50 ug | EUR 592 |
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 Antibody (HRP)) Anti-Glycoprotein Antibody (GP) Antibody (HRP) |
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| 20-abx319902 | Abbexa |
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 Antibody (FITC)) Anti-Glycoprotein Antibody (GP) Antibody (FITC) |
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| 20-abx319903 | Abbexa |
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 Antibody (Biotin)) Anti-Glycoprotein Antibody (GP) Antibody (Biotin) |
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| 20-abx319904 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (HRP) |
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| 20-abx319906 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (FITC) |
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| 20-abx319907 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (Biotin) |
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| 20-abx319908 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (HRP) |
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| 20-abx319914 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (FITC) |
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| 20-abx319915 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (Biotin) |
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| 20-abx319916 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (HRP) |
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| 20-abx319929 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (FITC) |
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| 20-abx319930 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody (Biotin) |
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| 20-abx319931 | Abbexa |
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 Antibody) Anti-Glycoprotein 210 Antibody (gp210) Antibody |
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| abx233571-100ug | Abbexa | 100 ug | EUR 481 |
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 Antibody (HRP)) Ly1 Antibody Reactive (LYAR) Antibody (HRP) |
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| 20-abx311666 | Abbexa |
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 Antibody (FITC)) Ly1 Antibody Reactive (LYAR) Antibody (FITC) |
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| 20-abx311667 | Abbexa |
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 Antibody (Biotin)) Ly1 Antibody Reactive (LYAR) Antibody (Biotin) |
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| 20-abx311668 | Abbexa |
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 Goat anti- human Antibody^Polyclonal antibody |
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| LSMab09896 | Lifescience Market | 100 ug | EUR 438 |
 Antibody for Human alpha Tubulin Antibody |
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| SPC-692D | Stressmarq | 0.1mg | EUR 354 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A390 | Stressmarq | 0.1mg | EUR 401 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A488 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A565 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 565. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A594 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 594. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A633 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 633. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A655 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 655. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A680 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 680. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-A700 | Stressmarq | 0.1mg | EUR 400 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 700. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-ALP | Stressmarq | 0.1mg | EUR 394 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Alkaline Phosphatase. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-APC | Stressmarq | 0.1mg | EUR 399 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC . |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-APCCY7 | Stressmarq | 0.1mg | EUR 471 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC/Cy7. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-BI | Stressmarq | 0.1mg | EUR 396 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Biotin. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-DY350 | Stressmarq | 0.1mg | EUR 414 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 350. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-DY405 | Stressmarq | 0.1mg | EUR 403 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 405. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-DY488 | Stressmarq | 0.1mg | EUR 393 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 488. |
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Antibody for Human alpha Tubulin Antibody |
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| SPC-692D-DY594 | Stressmarq | 0.1mg | EUR 395 |
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Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 594. |
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Irregular Homocysteine Metabolism: An Perception of Alzheimer’s Illness from DNA Methylation
Alzheimer’s illness (AD) is a persistent neurodegenerative illness within the central nervous system that has advanced pathogenesis within the aged. The present evaluation focuses on the epigenetic mechanisms of AD, in response to the newest findings. The most effective-characterized chromatin modifications in epigenetic mechanisms is DNA methylation. Extremely replicable knowledge reveals that AD incidence is usually accompanied by methylation degree adjustments of the AD-related gene.
Homocysteine (Hcy) is just not solely an intermediate product of one-carbon metabolism but in addition an vital impartial danger issue of AD; it may possibly have an effect on the cognitive perform of the mind by altering the one-carbon metabolism and interfering with the DNA methylation course of, leading to cerebrovascular illness. Usually, Hcy could also be an environmental issue that impacts AD by way of the DNA methylation pathway with a collection of adjustments in AD-related substance. This evaluation will think about the relation between DNA methylation and Hcy and take a look at to determine their rule within the pathophysiology of AD.
TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation
Hypoxia-inducible components are heterodimeric transcription components that play an important position in a cell’s capability to adapt to low oxygen. The von-Hippel Lindau tumor suppressor (pVHL), acts as a grasp regulator of HIF exercise, and its focusing on of prolyl hydroxylated HIF-α for proteasomal degradation beneath normoxia is considered a significant mechanism for pVHL tumor suppression and mobile response to oxygen.
Whether or not pVHL regulates different targets by the same mechanism is essentially unknown. Right here, we determine TET2/Three as novel targets of pVHL. pVHL induces proteasomal degradation of TET2/3, leading to decreased international 5-hydroxymethylcytosine ranges.
Conserved proline residues inside the LAP/LAP-like motifs of those two proteins are hydroxylated by the prolyl hydroxylase enzymes (PHD2/EGLN1 and PHD3/EGLN3), which is prerequisite for pVHL-mediated degradation. Utilizing zebrafish as a mannequin, we decided that international 5-hydroxymethylcytosine ranges are enhanced in vhl-null, egln1a/b-double null and egln3-null embryos.
Subsequently, we reveal a novel perform for the PHD-pVHL pathway in regulating TET protein stability and exercise. These knowledge prolong our understanding of how TET proteins are regulated and supply new perception into the mechanisms of pVHL in tumor suppression.
Level-of-care DNA testing by routinely and sequentially performing extraction, amplification and identification in a closed-type cassette
- Nucleic acid detection is vital for scientific diagnostics; nonetheless, it’s difficult to carry out genetic testing on the point-of-care because of the tedious steps concerned in DNA extraction and the chance of cross-contamination from amplicons.
- To realize a fully-automated and contamination-free nucleic acid detection, we suggest a closed-type cassette system which allows the next steps to be operated routinely and sequentially: pattern preparation based mostly on magnetic beads, goal amplification utilizing multiplex polymerase chain response, and colorimetric detection of amplicons utilizing a serial invasive response coupled with the aggregation of gold nanoparticle probes.
- The cassette was designed to be spherical and closed, and 10 targets in a pattern might be concurrently detected by the bare eye or utilizing a spectrophotometer within the system.
- As well as, a cassette-driven system was fabricated to switch reagents between wells, to regulate the temperature of every response, and to sense the color within the detection wells. The cassette system was delicate sufficient to detect 10 genotypes at 5 single nucleotide polymorphism websites associated to the anticoagulant’s utilization, through the use of a 0.5 µL blood pattern.
- The accuracy of the system was evaluated by detecting 12 entire blood samples, and the outcomes obtained have been according to these obtained utilizing pyrosequencing. The cassette is hermetic and the entire system is absolutely computerized; the one guide operation is the addition of the pattern to the cassette, performing point-of-care genetic testing in a sample-in/answer-out means.
 Antibody) DNA Ligase 4 (LIG4) Antibody |
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| abx234774-100ug | Abbexa | 100 ug | EUR 509 |
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DNA Ligase 4 (LIG4) Antibody |
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| abx330937-100ul | Abbexa | 100 ul | EUR 425 |
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DNA Ligase 4 (LIG4) Antibody |
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| 20-abx322926 | Abbexa |
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DNA Ligase 4 (LIG4) Antibody |
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| 20-abx324859 | Abbexa |
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DNA Ligase 4 (LIG4) Antibody |
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| 20-abx001451 | Abbexa |
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 ELISA Kit) Human DNA Ligase 4 (LIG4) ELISA Kit |
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| abx388272-96tests | Abbexa | 96 tests | EUR 911 |
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 Human DNA ligase 4, LIG4 ELISA KIT |
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| ELI-47684h | Lifescience Market | 96 Tests | EUR 824 |
 Mouse DNA ligase 4, Lig4 ELISA KIT |
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| ELI-32012m | Lifescience Market | 96 Tests | EUR 865 |
 Chicken DNA ligase 4, LIG4 ELISA KIT |
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| ELI-47798c | Lifescience Market | 96 Tests | EUR 928 |
 Antibody) DNA Ligase 4 Phospho-Thr650 (LIG4 pT650) Antibody |
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| 20-abx322874 | Abbexa |
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 DNA Ligase 4 antibody |
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| 70R-35788 | Fitzgerald | 100 ug | EUR 327 |
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Description: Rabbit polyclonal DNA Ligase 4 antibody |
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DNA Ligase 4 antibody |
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| 70R-50002 | Fitzgerald | 100 ul | EUR 244 |
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Description: Purified Polyclonal DNA Ligase 4 antibody |
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 Antibody) DNA Ligase 4 (pT650) Antibody |
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| abx216563-100ug | Abbexa | 100 ug | EUR 439 |
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 Antibody) DNA Ligase 4 (DNL4) Antibody |
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| 20-abx014021 | Abbexa |
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 DNA Ligase 4 Blocking Peptide |
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| 20-abx061782 | Abbexa |
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DNA Ligase 4 Blocking Peptide |
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| 20-abx062877 | Abbexa |
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 Recombinant T4 DNA Ligase |
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| 7-03622 | CHI Scientific | 20,000IU | Ask for price |
Recombinant T4 DNA Ligase |
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| 7-03623 | CHI Scientific | 100,000IU | Ask for price |
Recombinant T4 DNA Ligase |
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| 7-03624 | CHI Scientific | 500,000IU | Ask for price |
) T4 DNA Ligase (Recombinant) |
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| abx073011-100000IU | Abbexa | 100.000 IU | EUR 509 |
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T4 DNA Ligase (Recombinant) |
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| abx073011-20000IU | Abbexa | 20.000 IU | EUR 258 |
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T4 DNA Ligase (Recombinant) |
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| abx073011-500000IU | Abbexa | 500.000 IU | EUR 1539 |
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 Antibody) DNA Ligase 4 (Phospho-Thr650) Antibody |
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| 12457-100ul | SAB | 100ul | EUR 252 |
DNA Ligase 4 (Phospho-Thr650) Antibody |
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| 12457-50ul | SAB | 50ul | EUR 187 |
 Antibody) Phospho-DNA Ligase 4 (Thr650) Antibody |
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| AF8089 | Affbiotech | 200ul | EUR 376 |
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Description: DNA Ligase 4 (Phospho-Thr650) Antibody detects endogenous levels of DNA Ligase 4 only when phosphorylated at Thr650. |
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 Antibody) DNA Ligase 4 (Phospho- Thr650) Antibody |
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| ABF8089 | Lifescience Market | 100 ug | EUR 438 |
 Antibody) DNA Ligase I (DNA Ligase I) Antibody |
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| abx232431-100ug | Abbexa | 100 ug | EUR 481 |
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 T4 DNA Ligase) Recombinant (E.Coli) T4 DNA Ligase |
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| RP-374 | Alpha Diagnostics | 20 KU | EUR 164 |
 Blocking Peptide) Phospho-DNA Ligase 4 (Thr650) Blocking Peptide |
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| AF8089-BP | Affbiotech | 1mg | EUR 195 |
 T4 DNA ligase |
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| 402-002 | GeneOn | 400 WEISS UNITS | EUR 63 |
T4 DNA ligase |
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| 402-010 | GeneOn | 2000 WEISS UNITS | EUR 154 |
 T4 DNA Ligase |
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| abx098136-10kU | Abbexa | 10 kU | EUR 321 |
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T4 DNA Ligase |
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| abx098136-20Ku | Abbexa | 20 Ku | EUR 398 |
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 DNA ligase Antibody |
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| 20-abx110554 | Abbexa |
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 IL-4 Interleukin 4 Human Recombinant Protein, Yeast |
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| PROTP05112-4 | BosterBio | Regular: 10ug | EUR 317 |
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Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques. |
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 DNA Ligase IV recombinant monoclonal antibody |
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| A5820 | Bimake | 100ul X 3 | EUR 595 |
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Description: A recombinant monoclonal antibody from rabbit against human DNA Ligase IV for WB, IHC, IF,ELISA |
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 Polyclonal Conjugated Antibody) DNA Ligase 4 (Phospho-Thr650) Polyclonal Conjugated Antibody |
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| C12457 | SAB | 100ul | EUR 397 |
) Human DNA ligase 1 (LIG1) |
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| 1-CSB-EP012930HU | Cusabio |
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Description: Recombinant Human DNA ligase 1(LIG1) expressed in E.coli |
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 Recombinant Human 4-1BB Receptor Protein |
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| PROTQ07011-4 | BosterBio | 20ug | EUR 317 |
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Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor. |
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 Protein) Recombinant Human PF-4 (CXCL4) Protein |
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| PROTP02776-4 | BosterBio | 20ug | EUR 317 |
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Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. |
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 100 BP DNA LADDER, 500UL PER KIT |
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| M-DNA-100BP | CORNING | 1/pk | EUR 73 |
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Description: Bioscience Mol Bio; DNA Ladder |
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 1 KB DNA LADDER, 500UL PER KIT |
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| M-DNA-1KB | CORNING | 1/pk | EUR 70 |
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Description: Bioscience Mol Bio; DNA Ladder |
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 T4 DNA Ligase protein |
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| 30R-2898 | Fitzgerald | 250 units | EUR 224 |
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Description: Purified recombinant Human T4 DNA Ligase protein |
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 DNA ligase 3 antibody |
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| 22508-100ul | SAB | 100ul | EUR 390 |
DNA ligase 3 antibody |
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| 22940-100ul | SAB | 100ul | EUR 390 |
DNA ligase 3 antibody |
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| 70R-12710 | Fitzgerald | 100 ul | EUR 457 |
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Description: Affinity purified Rabbit polyclonal DNA ligase 3 antibody |
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DNA ligase 3 antibody |
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| 70R-12712 | Fitzgerald | 100 ul | EUR 457 |
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Description: Affinity purified Rabbit polyclonal DNA ligase 3 antibody |
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 DNA ligase IV Antibody |
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| 35335-100ul | SAB | 100ul | EUR 390 |
 DNA Ligase IV Antibody |
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| 49667-100ul | SAB | 100ul | EUR 333 |
DNA Ligase IV Antibody |
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| 49667-50ul | SAB | 50ul | EUR 239 |
 DNA Ligase I Antibody |
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| 49797-100ul | SAB | 100ul | EUR 333 |
DNA Ligase I Antibody |
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| 49797-50ul | SAB | 50ul | EUR 239 |
 T4 DNA Ligase Buffer |
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| 9102-1 | Biovision | EUR 88 | |
) DNA ligase Antibody (Biotin) |
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| 20-abx106283 | Abbexa |
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) DNA ligase Antibody (FITC) |
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| 20-abx107697 | Abbexa |
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) DNA ligase Antibody (HRP) |
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| 20-abx109115 | Abbexa |
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 DNA Ligase 1 Antibody |
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| 20-abx141113 | Abbexa |
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 DNA Ligase 3 Antibody |
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| 20-abx141114 | Abbexa |
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 E. coli DNA Ligase |
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| M1217-100 | Biovision | EUR 321 | |
) T4 DNA Ligase (Rapid) |
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| N103-01 | Vazyme | 600,000 U | EUR 563 |
) T4 DNA Ligase (40000U) |
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| 9K-005-0002 | Bio Basic | 40000U | EUR 292.73 |
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 anti-DNA Ligase I |
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| YF-PA12953 | Abfrontier | 50 ul | EUR 363 |
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Description: Mouse polyclonal to DNA Ligase I |
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anti-DNA Ligase I |
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| YF-PA24084 | Abfrontier | 50 ul | EUR 334 |
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Description: Mouse polyclonal to DNA Ligase I |
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 anti-DNA Ligase III |
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| YF-PA24085 | Abfrontier | 50 ul | EUR 334 |
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Description: Mouse polyclonal to DNA Ligase III |
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 pUC57- T4 DNA Ligase |
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| PVT10516 | Lifescience Market | 2 ug | EUR 266 |
 T4 DNA Ligase Plasmid |
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| PVT7008 | Lifescience Market | 2 ug | EUR 512 |
) Recombinant ATP Dependent DNA ligase I (LIG1) |
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| 4-RPB269Hu01 | Cloud-Clone |
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Description: Recombinant Human ATP Dependent DNA ligase I expressed in: E.coli |
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Recombinant ATP Dependent DNA ligase I (LIG1) |
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| 4-RPB269Ra01 | Cloud-Clone |
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Description: Recombinant Rat ATP Dependent DNA ligase I expressed in: E.coli |
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) Recombinant Treponema pallidum p15 (partial) |
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| 7-07552 | CHI Scientific | 100µg | Ask for price |
Recombinant Treponema pallidum p15 (partial) |
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| 7-07553 | CHI Scientific | 500µg | Ask for price |
Recombinant Treponema pallidum p15 (partial) |
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| 7-07554 | CHI Scientific | 1000µg | Ask for price |
) Recombinant Treponema pallidum p17 (Partial) |
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| 7-07564 | CHI Scientific | 100µg | Ask for price |
Recombinant Treponema pallidum p17 (Partial) |
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| 7-07565 | CHI Scientific | 500µg | Ask for price |
Recombinant Treponema pallidum p17 (Partial) |
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| 7-07566 | CHI Scientific | 1000µg | Ask for price |
) Recombinant Treponema pallidum p47 (Partial) |
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| 7-07576 | CHI Scientific | 100µg | Ask for price |
Recombinant Treponema pallidum p47 (Partial) |
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| 7-07577 | CHI Scientific | 500µg | Ask for price |
Recombinant Treponema pallidum p47 (Partial) |
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| 7-07578 | CHI Scientific | 1000µg | Ask for price |
) Recombinant Treponema pallidum TmpA (Partial) |
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| 7-07579 | CHI Scientific | 100µg | Ask for price |
Recombinant Treponema pallidum TmpA (Partial) |
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| 7-07580 | CHI Scientific | 500µg | Ask for price |
Recombinant Treponema pallidum TmpA (Partial) |
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| 7-07581 | CHI Scientific | 1000µg | Ask for price |
 Feline IL-4 Recombinant Protein |
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| R00230-4 | BosterBio | 5ug/vial | EUR 259 |
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Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast. |
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 DNA Ligase I ELISA KIT|Human |
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| EF009143 | Lifescience Market | 96 Tests | EUR 689 |
 Recombinant Human DNA ligase 1 Protein, GST, E.coli-100ug |
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| QP6308-ec-100ug | EnQuireBio | 100ug | EUR 408 |
 Recombinant Human DNA ligase 1 Protein, GST, E.coli-10ug |
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| QP6308-ec-10ug | EnQuireBio | 10ug | EUR 200 |
 Recombinant Human DNA ligase 1 Protein, GST, E.coli-1mg |
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| QP6308-ec-1mg | EnQuireBio | 1mg | EUR 1632 |
 Recombinant Human DNA ligase 1 Protein, GST, E.coli-200ug |
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| QP6308-ec-200ug | EnQuireBio | 200ug | EUR 634 |
 Recombinant Human DNA ligase 1 Protein, GST, E.coli-500ug |
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| QP6308-ec-500ug | EnQuireBio | 500ug | EUR 1060 |
 Recombinant Human DNA ligase 1 Protein, GST, E.coli-50ug |
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| QP6308-ec-50ug | EnQuireBio | 50ug | EUR 263 |
 Recombinant E.coli DNA ligase Protein, His, E.coli-100ug |
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| QP7075-100ug | EnQuireBio | 100ug | EUR 771 |
 Recombinant E.coli DNA ligase Protein, His, E.coli-10ug |
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| QP7075-10ug | EnQuireBio | 10ug | EUR 355 |