Stearoyl-CoA Desaturase 1 Activity Determines the Maintenance of DNMT1-Mediated DNA Methylation Patterns in Pancreatic β-Cells
Metabolic stress, corresponding to lipotoxicity, impacts the DNA methylation profile in pancreatic β-cells and thus contributes to β-cell failure and the development of sort 2 diabetes (T2D). Stearoyl-CoA desaturase 1 (SCD1) is a rate-limiting enzyme that’s concerned in monounsaturated fatty acid synthesis, which protects pancreatic β-cells towards lipotoxicity. The current research discovered that SCD1 can also be required for the institution and upkeep of DNA methylation patterns in β-cells.
- We confirmed that SCD1 inhibition/deficiency prompted DNA hypomethylation and adjusted the methyl group distribution inside chromosomes in β-cells. Decrease ranges of DNA methylation in SCD1-deficient β-cells have been adopted by decrease ranges of DNA methyltransferase 1 (DNMT1).
- We additionally discovered that the downregulation of SCD1 in pancreatic β-cells led to the activation of adenosine monophosphate-activated protein kinase (AMPK) and a rise within the exercise of the NAD-dependent deacetylase sirtuin-1 (SIRT1). Moreover, the bodily affiliation between DNMT1 and SIRT1 stimulated the deacetylation of DNMT1 beneath circumstances of SCD1 inhibition/downregulation, suggesting a mechanism by which SCD1 exerts management over DNMT1.
- We additionally discovered that SCD1-deficient β-cells that have been handled with compound c, an inhibitor of AMPK, have been characterised by larger ranges of each international DNA methylation and DNMT1 protein expression in contrast with untreated cells.
- Subsequently, we discovered that activation of the AMPK/SIRT1 signaling pathway mediates the impact of SCD1 inhibition/deficiency on DNA methylation standing in pancreatic β-cells. Altogether, these findings recommend that SCD1 is a gatekeeper that protects β-cells towards the lipid-derived lack of DNA methylation and supply mechanistic insights into the mechanism by which SCD1 regulates DNA methylation patterns in β-cells and T2D-relevant tissues.

Pneumocystis carinii antibody |
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10R-2447 | 100 ug | EUR 391 |
Description: Mouse monoclonal Pneumocystis carinii antibody |
Pneumocystis carinii antibody |
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10R-2448 | 100 ug | EUR 391 |
Description: Mouse monoclonal Pneumocystis carinii antibody |
Pneumocystis carinii antibody |
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10R-2449 | 100 ug | EUR 391 |
Description: Mouse monoclonal Pneumocystis carinii antibody |
Pneumocystis jiroveci PCR kit |
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PCR-H440-48D | 50T | EUR 453 |
Pneumocystis jiroveci PCR kit |
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PCR-H440-96D | 100T | EUR 572 |
MDV Real-Time PCR Kit |
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PD65-06 | 96t | EUR 1553.6 |
Description: Please check the datasheet of MDV Real-Time PCR Kit before using the test. |
ALV Real-Time PCR Kit |
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PD65-15 | 96t | EUR 1724.4 |
Description: Please check the datasheet of ALV Real-Time PCR Kit before using the test. |
Anti-Human Pneumocystis Carinii antibody |
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STJ16100417 | 1 mL | EUR 747 |
0.2ML CLEAR STRIP CAPS FOR REAL TIME PCR |
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PCR-2CP-RT-C | 125/pk | EUR 223 |
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen |
hsa-mir-521 Real-time RT-PCR Detection Kit |
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20-abx097600 |
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dsGreen for Real-Time PCR, 100×, 100 uL |
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11010 | 100 uL | EUR 59 |
dsGreen for Real-Time PCR, 100×, 1 mL |
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41010 | 1 mL | EUR 249 |
dsGreen for Real-Time PCR, 100×, 1.5 mL |
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51010 | 1.5 mL | EUR 331 |
dsGreen for Real-Time PCR, 100×, 2 mL |
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61010 | 2 mL | EUR 363 |
dsGreen for Real-Time PCR, 100×, 10 mL |
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81010 | 10 mL | EUR 869 |
dsGreen for Real-Time PCR, 100×, 50 mL |
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91010 | 50 mL | EUR 3169 |
dsGreen for Real-Time PCR, 100×, 5 mL |
||
71010 | 5 mL | EUR 625 |
Pneumocystis jiroveci RT PCR kit |
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RTq-H440-100D | 100T | EUR 717 |
Pneumocystis jiroveci RT PCR kit |
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RTq-H440-150D | 150T | EUR 808 |
Pneumocystis jiroveci RT PCR kit |
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RTq-H440-50D | 50T | EUR 598 |
PMA Real-Time PCR Bacterial Viability Kit - Salmonella enterica (invA) |
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31033 | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - Mycobacterium tuberculosis (groEL2) |
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31034 | 1kit | EUR 399 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - Staphylococcus aureus (nuc) |
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31035 | 1kit | EUR 399 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - Staphylococcus aureus (mecA) |
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31036 | 1kit | EUR 399 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - E. coli (uidA) |
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31050 | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - Listeria monocytogenes (hly) |
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31051 | 1kit | EUR 399 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - Legionella pneumophila (mip) |
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31053 | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
Pneumocystis jiroveci One-Step PCR kit |
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Oneq-H440-100D | 100T | EUR 866 |
Pneumocystis jiroveci One-Step PCR kit |
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Oneq-H440-150D | 150T | EUR 981 |
Pneumocystis jiroveci One-Step PCR kit |
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Oneq-H440-50D | 50T | EUR 718 |
Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit |
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RR-0478-02 | 25 tests/kit | EUR 991 |
Description: Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems. |
PMA Real-Time PCR Bacterial Viability Kit - Salmonella enterica (invA) PMAxx |
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31033-X | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - E. coli (uidA) PMAxx |
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31050-X | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
PMA Real-Time PCR Bacterial Viability Kit - Listeria monocytogenes (hly) PMAxx |
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31051-X | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
Human Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit |
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DD2H | 1 Kit | EUR 430 |
Mouse Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit |
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DD2M | 1 Kit | EUR 430 |
Rat Real-time PCR DNA Quantitation after QPCR DNA Damage Analysis Kit |
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DD2R | 1 Kit | EUR 430 |
hsa-mir-521 Real-Time RT-PCR Detection and U6 Calibration Kit |
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20-abx097601 |
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PMA Real-Time PCR Bacterial Viability Kit - E. coli O157:H7 (Z3276) |
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31037 | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
PCR Mycoplasma Detection Kit |
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M034-Kit | Kit | EUR 266 |
qPCR plate-foil universal (for Real-time PCR, Light Cycler 480) |
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A26979 | 1x100 pcs | EUR 186 |
Eztime Real - time PCRPremix 2x,Taqman |
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FYT105-100P | 100 Preps 1.25 ml | Ask for price |
Human Lung Cancer PCR Primer Library |
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HLUCPL-I | 1 set | EUR 548 |
Human Schwann Cell PCR Primer Library |
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HSCH-I | 1 set | EUR 548 |
PMA Real-Time PCR Bacterial Viability Kit - E. coli O157:H7 (Z3276) PMAxx |
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31037-X | 1kit | EUR 428 |
Description: Minimum order quantity: 1 unit of 1kit |
Pneumocystis Stain Kit |
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PCS-1 | 1 kit(s) | EUR 156 |
Pneumocystis Stain Kit |
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PCS-2 | 100 Slides | EUR 104 |
Pneumocystis Stain Kit |
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K1434-125 | EUR 425 |
Pneumocystis Stain Kit |
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K1434-30 | EUR 316 |
Eztime Real - time PCRPremix 2x,SYBR Green |
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FYT103-100P | 100 Preps 1.25 ml | Ask for price |
Eztime Real - time PCRPremix 2x,SYBR Green |
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FYT103-400P | 400 Preps 1.25 ml x 4 | Ask for price |
Eztime Real - time PCRPremix 2x,SYBRGreen , ROX |
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FYT104-100P | 100 Preps 1.25 ml | Ask for price |
Eztime Real - time PCRPremix 2x,SYBRGreen , ROX |
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FYT104-400P | 400 Preps 1.25 ml x 4 | Ask for price |
Eztime Real - time PCRPremix 2x,Taqman, ROX |
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FYT105-400P | 400 Preps 1.25 ml x 4 | Ask for price |
Eztime Real - time PCRPremix 2x,Taqman, ROX |
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FYT106-100P | 100 Preps 1.25 ml | Ask for price |
0,1ML THIN WALL TUBES 8 PER STRIP. CLEAR & REAL TIME STRIP CAPS |
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PCR-0108-LP-RT-C | 125/pk | EUR 709 |
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen |
0,1ML THIN WALL TUBES 8 PER STRIP. WHITE & REAL TIME STRIP CAPS |
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PCR-0108-LP-RT-W | 125/pk | EUR 770 |
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen |
Green Dye One Step qRT-PCR Master Mix For Quantitative Real Time PCR With ROX Dye |
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MB1004-100Reactions | 100 Reactions | EUR 327 |
hsa-let-7a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097603 |
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hsa-let-7b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097604 |
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hsa-let-7c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097605 |
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hsa-let-7d Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097606 |
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hsa-let-7e Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097607 |
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hsa-let-7f Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097608 |
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hsa-let-7g Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097609 |
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hsa-let-7i Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097610 |
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hsa-let-7f Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097611 |
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hsa-mir-1 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097612 |
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hsa-mir-7 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097613 |
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hsa-mir-9 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097614 |
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hsa-mir-9* Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097615 |
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hsa-mir-10a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097616 |
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hsa-mir-10b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097617 |
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hsa-mir-10a* Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097618 |
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hsa-mir-15a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097619 |
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hsa-mir-15b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097620 |
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hsa-mir-16 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097622 |
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hsa-mir-18a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097625 |
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hsa-mir-18b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097626 |
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hsa-mir-19a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097627 |
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hsa-mir-19b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097628 |
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hsa-mir-20a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097629 |
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hsa-mir-20b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097630 |
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hsa-mir-21 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097631 |
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hsa-mir-22 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097632 |
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hsa-mir-23a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097633 |
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hsa-mir-23b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097634 |
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hsa-mir-25 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097636 |
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hsa-mir-26a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097637 |
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hsa-mir-26b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097638 |
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hsa-mir-27a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097639 |
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hsa-mir-27b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097640 |
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hsa-mir-29a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097642 |
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hsa-mir-29b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097643 |
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hsa-mir-29c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097644 |
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hsa-mir-30a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097645 |
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hsa-mir-30b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097647 |
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hsa-mir-30c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit |
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20-abx097648 |
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Circulating Vitamin D Levels and DNA Repair Capacity in Four Molecular Subtypes of Women with Breast Cancer
Vitamin D regulates estrogen synthesis amongst different mechanisms concerned in breast most cancers (BC) growth; nonetheless, no proof has been discovered relating to its relationship with DNA restore capability (DRC). Subsequently, the target of this research was to elucidate whether or not DRC ranges are linked with plasma 25(OH)D ranges.
- BC circumstances and controls have been chosen from our BC cohort. DRC ranges have been assessed in lymphocytes by the host-cell reactivation assay. 25(OH)D ranges have been measured utilizing the UniCel DxI 600 Entry Immunoassay System. BC circumstances (n = 91) confirmed larger 25(OH)D ranges than the controls (n = 92) (p = 0.001).
- When stratifying BC circumstances and controls into high and low DRC classes, BC circumstances with low DRC (n = 74) had the best 25(OH)D ranges (p = 0.0001).
- A constructive correlation between 25(OH)D and DRC ranges was discovered for the controls (r = 0.215, p = 0.043) whereas a destructive correlation was discovered for BC circumstances (r = -0.236, p = 0.026). Important variations in 25(OH)D ranges have been noticed when stratifying by molecular subtypes (p = 0.0025).
- Our research supplies proof of a hyperlink between 25(OH)D and DRC in BC together with an outline of to how 25(OH)D ranges fluctuate throughout subtypes. The constructive correlation noticed within the management group means that 25(OH)D contributes in a different way to DRC ranges as soon as the malignancy is developed.
Intercourse-specific associations with DNA methylation in lung tissue show smoking interactions
Cigarette smoking impacts DNA methylation, however the investigation of sex-specific options of lung tissue DNA methylation in people who smoke has been restricted. Girls seem extra prone to cigarette smoke, and sometimes develop extra extreme lung illness at an earlier age with much less smoke publicity.
We aimed to analyse whether or not there are intercourse variations in DNA methylation in lung tissue and whether or not these DNA methylation marks work together with smoking. We collected lung tissue samples from former people who smoke who underwent lung tissue resection. 100 thirty samples from white topics have been included for this evaluation. Regression fashions for intercourse as a predictor of methylation have been adjusted for age, presence of COPD, smoking variables and technical batch variables revealed 710 related websites.
294 websites demonstrated sturdy sex-specific methylation associations in foetal lung tissue. Pathway evaluation recognized 6 nominally vital pathways together with the mitophagy pathway. Three CpG websites demonstrated a urged interplay between intercourse and pack-years of smoking: GPR132, ANKRD44 and C19orf60.
All of them have been nominally vital in each male- and female-specific fashions, and the impact estimates have been in reverse instructions for female and male; GPR132 demonstrated vital affiliation between DNA methylation and gene expression in lung tissue (P< 0.05). Intercourse-specific associations with DNA methylation in lung tissue are wide-spread and will reveal genes and pathways related to intercourse variations for lung damaging results of cigarette smoking.
GPCR RDC1 Antibody |
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49041-100ul | 100ul | EUR 333 |
GPCR RDC1 Antibody |
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49041-50ul | 50ul | EUR 239 |
anti-GPCR GPR62 |
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YF-PA26842 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR GPR62 |
anti-GPCR LOC51210 |
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YF-PA26875 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR LOC51210 |
anti-GPCR GPR3 |
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YF-PA12103 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR GPR3 |
anti-GPCR GPR34 |
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YF-PA12105 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR GPR34 |
anti-GPCR HM74 |
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YF-PA15914 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR HM74 |
anti-GPCR GPR146 |
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YF-PA21926 | 100 ug | EUR 403 |
Description: Rabbit polyclonal to Anti-GPCR GPR146 |
anti-GPCR MRGX2 |
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YF-PA22009 | 50 ug | EUR 363 |
Description: Mouse polyclonal to Anti-GPCR MRGX2 |
anti-GPCR LOC51210 |
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YF-PA22204 | 50 ul | EUR 363 |
Description: Mouse polyclonal to GPCR LOC51210 |
anti-GPCR LOC51210 |
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YF-PA22205 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR LOC51210 |
anti-GPCR LOC51210 |
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YF-PA22206 | 100 ul | EUR 403 |
Description: Rabbit polyclonal to GPCR LOC51210 |
anti-GPCR LOC51210 |
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YF-PA22207 | 100 ug | EUR 403 |
Description: Rabbit polyclonal to GPCR LOC51210 |
anti-GPCR 2037 |
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YF-PA22241 | 50 ug | EUR 363 |
Description: Mouse polyclonal to Anti-GPCR 2037 |
anti-GPCR GPR110 |
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YF-PA22867 | 50 ul | EUR 363 |
Description: Mouse polyclonal to GPCR GPR110 |
anti-GPCR GPR110 |
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YF-PA22868 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR GPR110 |
anti-GPCR GPR3 |
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YF-PA23809 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR GPR3 |
anti-GPCR SALPR |
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YF-PA26165 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR SALPR |
anti-GPCR EX33 |
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YF-PA26233 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR EX33 |
anti-GPCR GPRC5D |
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YF-PA26334 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR GPRC5D |
anti-GPCR LGR7 |
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YF-PA26522 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR LGR7 |
anti-GPCR LGR6 |
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YF-PA26523 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR LGR6 |
anti-GPCR TAS1R1 |
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YF-PA26658 | 50 ul | EUR 334 |
Description: Mouse polyclonal to GPCR TAS1R1 |
anti-GPCR C5L2 |
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YF-PA18412 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR C5L2 |
anti-GPCR SALPR |
||
YF-PA18968 | 50 ul | EUR 363 |
Description: Mouse polyclonal to GPCR SALPR |
anti-GPCR GPRC5D |
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YF-PA19735 | 50 ug | EUR 363 |
Description: Mouse polyclonal to GPCR GPRC5D |
Sheep GPCR ELISA Kit |
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ESG0026 | 96Tests | EUR 521 |
D-GPCR Polyclonal Antibody |
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ES2167-100ul | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA |
D-GPCR Polyclonal Antibody |
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ES2167-50ul | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA |
Rat GPCR ELISA Kit |
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ERG0026 | 96Tests | EUR 521 |
Rabbit GPCR ELISA Kit |
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ERTG0026 | 96Tests | EUR 521 |
Mouse GPCR ELISA Kit |
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EMG0026 | 96Tests | EUR 521 |
Monkey GPCR ELISA Kit |
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EMKG0026 | 96Tests | EUR 521 |
Porcine GPCR ELISA Kit |
||
EPG0026 | 96Tests | EUR 521 |
Human GPCR ELISA Kit |
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EHG0026 | 96Tests | EUR 521 |
Canine GPCR ELISA Kit |
||
ECG0026 | 96Tests | EUR 521 |
Chicken GPCR ELISA Kit |
||
ECKG0026 | 96Tests | EUR 521 |
Goat GPCR ELISA Kit |
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EGTG0026 | 96Tests | EUR 521 |
Bovine GPCR ELISA Kit |
||
EBG0026 | 96Tests | EUR 521 |
Anti-GPCR GPR40 Antibody |
||
STJ501005 | 100 µg | EUR 476 |
Anti-GPCR GPR3 Antibody |
||
STJ501253 | 100 µg | EUR 476 |
D-GPCR Polyclonal Antibody |
||
ABP51168-003ml | 0.03ml | EUR 158 |
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290 |
D-GPCR Polyclonal Antibody |
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ABP51168-01ml | 0.1ml | EUR 289 |
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290 |
D-GPCR Polyclonal Antibody |
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ABP51168-02ml | 0.2ml | EUR 414 |
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290 |
Anti-D-GPCR Antibody |
||
A12058 | 100ul | EUR 397 |
Description: Rabbit Polyclonal Antibody for D-GPCR Antibody (OR51E1) detection.tested for WB in Human. |
Anti-D-GPCR antibody |
||
STJ92705 | 200 µl | EUR 197 |
Description: Rabbit polyclonal to D-GPCR. |
DiscoveryProbe? GPCR Compound Library |
||
L1025-.1 | 100 uL/well(10 mM solution) | EUR 4736 |
DiscoveryProbe? GPCR Compound Library |
||
L1025-.25 | 250 uL/well(10 mM solution) | EUR 8518 |
DiscoveryProbe? GPCR Compound Library |
||
L1025-5 | 5 mg/well | EUR 11070 |
GPCR RDC1 Conjugated Antibody |
||
C49041 | 100ul | EUR 397 |
GPCR GPR86 Conjugated Antibody |
||
C48382 | 100ul | EUR 397 |
Anti-GPCR SALPR (1F10) |
||
YF-MA18467 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR SALPR |
Anti-GPCR EX33 (5C3) |
||
YF-MA18601 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR EX33 |
Anti-GPCR EX33 (5B7) |
||
YF-MA18602 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR EX33 |
Anti-GPCR EX33 (1D9) |
||
YF-MA18603 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR EX33 |
Anti-GPCR GPR48 (8F6) |
||
YF-MA18780 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR GPR48 |
Anti-GPCR GPRC5D (6D9) |
||
YF-MA18788 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR GPRC5D |
Anti-GPCR LOC51210 (6D7) |
||
YF-MA19845 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR LOC51210 |
Anti-GPCR LGR7 (3E3) |
||
YF-MA11622 | 100 ug | EUR 363 |
Description: Mouse monoclonal to GPCR LGR7 |
Anserini GPCR-APJ ELISA Kit |
||
EAG0026 | 96Tests | EUR 521 |
Guinea Pig GPCR ELISA Kit |
||
EGG0026 | 96Tests | EUR 521 |
Anti-GPCR GPR40 Antibody BIOTIN |
||
STJ501006 | 100 µg | EUR 586 |
Anti-GPCR GPR40 Antibody FITC |
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STJ501007 | 100 µg | EUR 586 |
Anti-GPCR GPR3 Antibody BIOTIN |
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STJ501254 | 100 µg | EUR 586 |
Anti-GPCR GPR3 Antibody FITC |
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STJ501255 | 100 µg | EUR 586 |
Anti-GPCR GPR40/FFAR1 Antibody |
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A01349-2 | 100ug/vial | EUR 294 |
Anti-GPCR LGR8/RXFP2 Antibody |
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A04848-1 | 100ug/vial | EUR 334 |
Anti-LGR6/Gpcr Lgr6 Antibody |
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A05990 | 100ul | EUR 397 |
Description: Rabbit Polyclonal LGR6/Gpcr Lgr6 Antibody. Validated in IHC and tested in Human, Mouse, Rat. |
Anti-GPCR GPR7/NPBWR1 Antibody |
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A08247-1 | 100ug/vial | EUR 294 |
Anti-GPR151/Gpcr 2037 Antibody |
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A14582 | 100ul | EUR 397 |
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-GPR151/Gpcr 2037 Antibody |
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A30814 | 100ul | EUR 397 |
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in IF, WB and tested in Mouse, Rat. |
anti-5-oxo-ETE GPCR |
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YF-PA22585 | 50 ug | EUR 363 |
Description: Mouse polyclonal to 5-oxo-ETE GPCR |
Phosphatase Orphan-2 (Recombinant) |
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20-abx073747 |
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Phosphatase Orphan-1 (Recombinant) |
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20-abx073910 |
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DiscoveryProbe? GPCR/G protein-related Compounds Panel |
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L1009-5 | 5 mg/well | EUR 6035 |
Description: A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc. |
Recombinant RAR Related Orphan Receptor Alpha (RORa) |
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4-RPD947Hu01 |
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Description: Recombinant Human RAR Related Orphan Receptor Alpha expressed in: E.coli |
Recombinant RAR Related Orphan Receptor Gamma (RORg) |
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4-RPD949Hu01 |
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Description: Recombinant Human RAR Related Orphan Receptor Gamma expressed in: E.coli |
Recombinant Neuron Derived Orphan Receptor 1 (NOR1) |
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4-RPC675Ra01 |
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Description: Recombinant Rat Neuron Derived Orphan Receptor 1 expressed in: E.coli |
PHOSPHO2 Phosphatase Orphan-2 Human Recombinant Protein |
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PROTQ8TCD6 | Regular: 10ug | EUR 317 |
Description: PHOSPHO2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (1-241) and having a molecular mass of 30.3kDa.;PHOSPHO2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
PHOSPHO1 Phosphatase Orphan-1 Human Recombinant Protein |
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PROTQ8TCT1 | Regular: 10ug | EUR 317 |
Description: Human Phospho1 Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 295 amino acids and having a molecular mass of 31.3 kDa. The Human Phospho1 is fused to a 14 aa His tag at N-Terminus. Human Phosphocholine Phosphatase is purified by proprietary chromatographic techniques. |
Neuron Derived Orphan Receptor 1 (NOR1) Antibody |
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20-abx130085 |
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Rar-Related Orphan Receptor A (RORA) Antibody |
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20-abx115045 |
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Rar-Related Orphan Receptor B (RORB) Antibody |
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20-abx115046 |
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Rar-Related Orphan Receptor C (RORC) Antibody |
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20-abx115047 |
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RAR Related Orphan Receptor Alpha (RORA) Antibody |
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20-abx119555 |
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Intermediate Filament Family Orphan 1 (IFFO1) Antibody |
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20-abx113262 |
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RAR Related Orphan Receptor Alpha (RORA) Antibody |
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20-abx338779 |
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RAR Related Orphan Receptor Alpha (RORa) Antibody |
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20-abx103508 |
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RAR Related Orphan Receptor Gamma (RORg) Antibody |
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20-abx103509 |
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Intermediate Filament Family Orphan 1 (IFFO1) Antibody |
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abx037159-100ug | 100 ug | EUR 391 |
Recombinant Human RAR-Related Orphan Receptor C |
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7-06163 | 5µg | Ask for price |
Recombinant Human RAR-Related Orphan Receptor C |
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7-06164 | 20µg | Ask for price |
Recombinant Human RAR-Related Orphan Receptor C |
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7-06165 | 1mg | Ask for price |
RAR Related Orphan Receptor Alpha (RORA) Antibody |
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20-abx005288 |
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